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The Colibactin Genotoxin Generates DNA Interstrand Cross-Links in Infected Cells

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ABSTRACT Colibactins are hybrid polyketide-nonribosomal peptides produced by Escherichia coli. Klebsiella pneumoniae. and other Enterobacteriaceae harboring the pks genomic island. These genotoxic metabolites are produced by pks-encoded peptide-polyketide synthases as inactive prodrugs called precolibactins. https://www.cosmeticssquadets.shop/product-category/lip-tint/
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