(1) Background: Sutures with triclosan (TS) are used to reduce the risk of surgical site infections (SSI). but most clinical trials are inconclusive. The traceability of SSI risk to antimicrobial activity in operated tissues is needed. (2) Objectives: This study aimed to predict triclosan antistaphylococcal activity in operated tissues. https://www.rxkaitori.com/product-category/led-emergency-kits/